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Hepatic Impairment . The pharmacokinetics of ropinirole have not been studied in patients with hepatic impairment. Because ropinirole is extensively metabolized by the liver.these patients may have higher plasma levels and lower clearance requip depression treatment ropinirole than patients with normal hepatic function.

If you are taking this for Parkinson’s and you miss a dose.take it as soon as you remember. If it is almost time for the next dose.skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

In clinical trials of patients treated for RLS with doses up to 4 mg once daily.REQUIP was discontinued without requip depression treatment taper.

Additionally.ropinirole is also used to treat restless legs syndrome (RLS). It may improve your sleep by decreasing the urge to move your legs as well as decrease the uncomfortable feelings in the legs.

You may have increased sexual urges.unusual urges to gamble.or other intense urges while taking this medicine. Talk with your doctor if this occurs.

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no indication of an effect on development of the conceptus was observed in rabbits when a maternally toxic dose of requip pd was administered alone 20 mg kg day, 16 times the maximum recommended human dose on a mg m 2 basis .